On Sawyer's Variable

1 Sawyers NEW

understanding of how oncogene and tumour suppressor gene networks influence the decisions of cancer cells to proliferate or die (Fig. 1). These decisions are further influenced by the tumour microenvironment and stress signals, such as DNA damage. Moreover, recent work suggests that a subpopulation of cancer cells with stem-cell-like properties may be critical for triggering tumour development....

On the first variable Zagreb index

‎The first variable Zagreb index of graph $G$ is defined as‎ ‎begin{eqnarray*}‎ ‎M_{1,lambda}(G)=sum_{vin V(G)}d(v)^{2lambda}‎, ‎end{eqnarray*}‎ ‎where $lambda$ is a real number and $d(v)$ is the degree of‎ ‎vertex $v$‎. ‎In this paper‎, ‎some upper and lower bounds for the distribution function and expected value of this index in random increasing trees (rec...

Brian Druker and Charles Sawyers receive the 2011 ASCI/Stanley J. Korsmeyer Award.

Chronic myelogenous leukemia (CML) was the first cancer to be linked to a clearly defined genetic defect, a chromosomal translocation that generates a constitutively active tyrosine kinase. In the 1990s, Brian Druker and Charles Sawyers (Figure 1) collaborated to develop the targeted therapies that transformed CML from a fatal disease to one that boasts a 90% cure rate. Their work has been wide...

Forest Entomology Pine Sawyers (Coleoptera: Cerambycidae) Attracted to a-Pinene, Monochamol, and Ipsenol in North America

Detection tools are needed for Monochamus species (Coleoptera: Cerambycidae) because they are known to introduce pine wilt disease by vectoring nematodes in Asia, Europe, and North America. In 2012–2014, we examined the effects of the semiochemicals monochamol and ipsenol on the flight responses of the sawyer beetles Monochamus carolinensis (Olivier), Monochamus clamator (LeConte), Monochamus m...

On the Random Variable